Oral folic acid and vitamin B-12 supplementation to prevent cognitive decline.
نویسنده
چکیده
REFERENCES 1. Clifton PM. Palm oil and LDL cholesterol. Am J Clin Nutr 2011; 94:1392–3. 2. Tholstrup T, Hjerpsted J, Raff M. Palm olein increases plasma cholesterol moderately compared with olive oil in healthy individuals. Am J Clin Nutr 2011;94:1426–32. 3. Renaud SC, Ruf JC, Petithory D. The positional distribution of fattyacids in palm oil and lard influences their biologic effects in rats. J Nutr 1995;125:229–37. 4. Hunter JE. Studies on effects of dietary fatty acids as related to their position on triglycerides. Lipids 2001;36:655–68.
منابع مشابه
Oral folic acid and vitamin B-12 supplementation to prevent cognitive decline in community-dwelling older adults with depressive symptoms--the Beyond Ageing Project: a randomized controlled trial.
BACKGROUND Evidence remains unclear as to whether folic acid (FA) and vitamin B-12 supplementation is effective in reducing depressive symptoms. OBJECTIVES The objective was to determine whether oral FA + vitamin B-12 supplementation prevented cognitive decline in a cohort of community-dwelling older adults with elevated psychological distress. DESIGN A randomized controlled trial (RCT) wit...
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BACKGROUND Vitamin B-12 deficiency is associated with cognitive impairment in older people. However, evidence from randomized trials of the effects of vitamin B-12 supplementation on cognitive function is limited and inconclusive. OBJECTIVE The objective was to investigate whether daily supplementation with high doses of oral vitamin B-12 alone or in combination with folic acid has any benefi...
متن کاملEffect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial.
BACKGROUND Low folate and raised homocysteine concentrations in blood are associated with poor cognitive performance in the general population. As part of the FACIT trial to assess the effect of folic acid on markers of atherosclerosis in men and women aged 50-70 years with raised plasma total homocysteine and normal serum vitamin B12 at screening, we report here the findings for the secondary ...
متن کاملVitamin B12 and cognitive function: an evidence-based analysis.
BACKGROUND More than 2.9 million serum vitamin B12 tests were performed in 2010 in Ontario at a cost of $40 million. Vitamin B12 deficiency has been associated with a few neurocognitive disorders. OBJECTIVE To determine the clinical utility of B12 testing in patients with suspected dementia or cognitive decline. METHODS Three questions were addressed: Is there an association between vitamin...
متن کاملاثر مکمل یاری با اسیدفولیک و ویتامین 12B بر هوموسیستئین بیماران همودیالیزی
Background: Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. The frequency of hyperhomocysteinemia is higher in hemodialysis (HD) patients than the general population. The objective of this study is to assess the efficacy of high-dose folic acid supplementation with and without vitamin B12 on lowering plasma total homocysteine (tHcy) concentrations in HD patients....
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ورودعنوان ژورنال:
- The American journal of clinical nutrition
دوره 95 5 شماره
صفحات -
تاریخ انتشار 2012